Dawei Zhou

发布者:禇佳强发布时间:2016-04-29浏览次数:113

Department: TEDA School of Biological Sciences and Biotechnology
Address: 23, HongDa Street, TEDA, Tianjin 300457, P. R. China
Phone: 86-22-66229544
E-mail: daweizhou@nankai.edu.cn


Professional Education


  • 1985-1989  B.S. in Organic Chemistry, Nankai University, Tianjin, China

  • 1989-1992  M. Sc. in Organometallic Chemistry, Nankai University, Tianjin, China

  • 2000-2003  Ph.D. in Pharmaceutical analysis, Shenyang Pharmaceutical University, Shenyang , China

  • 2003-2005 Postdoctoral Fellow in Pharmaceutical analysis, Tianjin University, Tianjin, China  

  • 2005-     Associate Professor, TEDA Institute of Biological Sciences and Biotechnology, Nankai University, Tianjin, China


Research Area


Her research lies at the crossroads of organic and biological chemistry, with

particular emphasis on biosynthetic pathway and enzymology of complex carbohydrate polymers, and basic biochemical characterization of carbohydrate active microbial glycosyltransferases.


Representative Publications

1.Zhou DW, Chen C, Xu LL, Utkina N , Danilov L, Torgov V, Veselovsky V, Liu B, Feng, L. (2016)Mass spectrometric characterization of a two-glycosyltransferase tandem reaction for assembly of tetrasaccharide repeating unit of Escherichia coli O77 O-antigen. Carbohydr. Res. 424, 24-29.

2.Xu YY, Dong CY, Zhou DW*.(2016)Characterization of biosynthetic pathway of the dTDP-L-Rha by electrospray ionization tandem Mass Spectrometry. J Chinese Mass Sp Soc, 37(1), 17-22.

3.Zhou DW*, Utkina N , Li DG, Dong CY, Druzhinina T, Veselovsky V, Liu B.(2013) Biochemical characterization of a new β-1,3-galactosyltransferase WbuP from Escherichia coliO114 that catalyzes the second step in O-antigen repeating-unit.Carbohydr. Res. 381, 43-50.

4.Li DG, Liu B, Zhou DW*(2013) Structural characterization of enzymatic products in the dTDP-d-Qui4NFo biosynthetic pathway using electrospray ionization tandem mass spectrometry. Rapid Commun mass sp. 27(6), 671-680.

5.Zhou DW*, Liu B, Wu JL, Qi YY(2013) Monitoring of Unusual Sugar Biosynthesis Enzyme Reaction by MALDI-TOF Mass Spectrometry. Chinese J Anal Chem, 41(1): 115-118.

6.Liu B, Chen M, Perepelov AV, Liu J, Ovchinnikova OC,Zhou DW, Feng L, Rozalski A, Knirel YA, Wang L(2012) . Genetic analysis of the O-antigen of Providencia alcalifaciens O30 and biochemical characterization of a formyltransferase involved in the synthesis ofa Qui4N derivative. Glycobiology,22(9), 1236-1244

7.Zhou DW *, Liu B, Wu JL, Hu B, Qi YY.(2011) Differentiation of Specific Function of Glycosyltransferase Gene by Matrix Assisted Laser Desorption-Time of FIight-Mass Spectrometry. Chinese J Anal Chem, 39(1): 99-102.

8.Zhou DW *, Liu B, Wu JL, Hu B, Qi YY.(2011) Monitoring of Glycosyltransferase Reactions by MALDI-TOF Mass Spectrometry. J Chinese Mass Sp Soc, 32(4), 218-224.

9.Zhou DW *, Hu B, Liu B, Wu JL, Han YF.(2010) Structure Elucidation of Product of β-1,3-Glucosyltransferase Encoded by wfgD Gene in Escherichia Coli O152 Using Mass Spectrometry. Chinese J Anal Chem, 38(2), 225-228.

10.Zhou DW, Li FM. (2004) Protein binding study of clozapine by capillary electrophoresis in the frontal analysis mode.J. Pharm. Biomed. Anal., 35, 879-885.

11.Li FM, Zhou DW, Guo XJ.(2003) Study on protein binding of Ketoprofen using capillary electrophoresis frontal analysis compared with liquid chromatography frontal analysis. J Chromatogr Sci., 41(3), 137-141.