冯露

发布者:禇佳强发布时间:2016-04-07浏览次数:2059

冯露

学历: 博士
职称: 长江学者特聘教授、杰青
专业方向: 1)细菌表面多糖抗原基因的功能和分子进化的研究; 2)微生物基因组学和功能基因组学的研究。3)重要病原微生物特异分子标识的筛选。
招生专业: 微生物学、生物化学与分子生物学
人员简介:

冯露,女, 博士生导师。1963年出生,1983年获江南大学学士学位,1994年获悉尼大学硕士学位,2001年获悉尼大学博士学位。1983年至1988年在天津工业微生物所工作;1989年至2002年在澳大利亚悉尼大学农学院学习和工作(其中1992-1994硕士在学,1998-2001博士在学,其余时间受聘工作)。2003年至今在南开大学工作,现任南开大学泰达生物技术研究院教授。2005年入选教育部新世纪优秀人才,2008年获国家杰出青年基金,2009年入选教育部长江学者;2008年被评为天津市优秀留学人员。

主要研究方向:1)细菌表面多糖抗原基因的功能和分子进化的研究; 2)微生物基因组学和功能基因组学的研究。3)重要病原微生物特异分子标识的筛选。至今共发表SCI收录论文110篇(总影响因子410,24篇为通讯作者,9篇为第一作者,2篇为第一兼通讯作者)。

    Email:fenglu63@nankai.edu.cn ; 电话:022-66229592

第一和通讯文章列表(标*为通讯作者):

  1. Lu Feng, Sof’ya N. Senchenkova, Jinghua Yang, Alexander S. Shashkov, Jiang Tao, Hongjie Guo, Jiansong Cheng, Yi Ren, Yuriy A. Knirel, Peter R. Reeves, Lei Wang*. Synthesis of the heteropolysaccharide O antigen of Escherichia coli O52 requires an ABC transporter: structural and genetic evidence. Journal of Bacteriology. 2004.186(14), 4510-19.

  2. Lu Feng, Wei Wang, Jiang Tao, Hongjie Guo, Gladys Krause, Lothor Beutin, Lei Wang*. Identification of Escherichia coli O114 O-antigen gene cluster and development of an O114 serogroup-specific PCR assay. Journal of Clinical Microbiology. 2004.42(8), 3799-804.

  3. Lu Feng, Sof’ya N. Senchenkova, Jinghua Yang, Alexander S. Shashkov, Jiang Tao, Hongjie Guo, Guang Zhao, Yuriy A. Knirel, Peter R. Reeves, Lei Wang*.Structural and genetic characterization of the Shigella boydii type 13 O antigen. Journal of Bacteriology. 2004. 186(2), 383-92.

  4. Lu Feng, Jiang Tao, Hongjie Guo, Jianguo Xu, Yayue Li, Fedousi Rezwan, Peter R. Reeves, Lei Wang*. Structure of the Shigella dysenteriae 7 O antigen gene cluster and identification of its antigen specific genes. Microbial Pathogenesis. 2004.36(2), 109-15.

  5. Lu Feng, Sof’ya N. Senchenkova, Jiang Tao, Alexander S. Shashkov, Bin Liu, Sergei D. Shevelev, Peter R. Reeves, Jianguo Xu, Yuriy A. Knirel, Lei Wang*. Structural and genetic characterization of enterohemorrhagic Escherichia coli O145 O antigen and development of an O145 serogroup-specific PCR assay. Journal of Bacteriology. 2005.187(2), 758-64.

  6. Lu Feng*, Weiqing Han, Quan Wang, David A. Bastin, Lei Wang*. Characterization of Escherichia coli O86 O-antigen Gene Cluster and Identification of O86 Specific Genes. Veterinary Microbiology. 2005.106(3-4), 241-48.

  7. Jiang Tao, Lei Wang, Dan Liu, Yayue Li, David A.Bastin, Yunqi Geng, Lu Feng*. Molecular Analysis of Shigella boydii O1 O-antigen gene cluster and its PCR typing. Canadian Journal of Microbiology. 2005.51(5), 387-92.

  8. Hongjie Guo, Qingke Kong, Jiansong Cheng, Lei Wang*, Lu Feng*. Characterization of the E. coli O59 and O155 O-antigen gene clusters: the atypical wzx genes are evolutionary relate. FEMS Microbiology Letters. 2005. 248(2), 153-61.

  9. Lu Feng, Sof' ya N Senchenkova, Wei Wang, Alexander S Shashkov, Bin Liu, Sergei D.Shevelev, Dan Liu, Yuriy A. Knirel, Lei Wang*. Structural and genetic characterization of the Shigella boydii type 18 O antigen. Gene. 2005.355, 79-86.

  10. Lei Wang, Bin Liu , Qingke Kong, Hartmut Steinrück, Gladys Krause, Lothar Beutin, Lu Feng*. Molecular Markers for Detection of Pathogenic Escherichia coli Strains Belonging to Serogroups O138 and O139. Veterinary Microbiology. 2005.111(3-4), 181-190.

  11. Lei Wang*, Yun Tang, Shuo Wang, Ru-Lin Liu, Mu-Zhi Liu, Yan Zhang, Feng-Lai Liang, Lu Feng*. Isolation and Characterization of a Novel Thermophilic Bacillus Strain Degrading Long-Chain n-Alkanes. Extremophiles. 2006. 10(4), 347-356.

  12. Linyan Wen, Quan Wang, Yayue Li, Fanrong Kong, Gwendolyn L. Gilbert, Boyang Cao, Lei Wang, Lu Feng*. Use of a Serotype-Specific DNA Microarray for Identification of Group B Streptococcus (Streptococcus agalactiae). Journal of Clinical Microbiology. 2006. 44(4), 1447-52.

  13. Jiansong Cheng, Quan Wang, Wei Wang, Ying Wang, Lei Wang, Lu Feng*. Characterization of E. coli O24 and O56 O antigen gene clusters reveals a complex evolutionary history of the O24 gene cluster. Current Microbiology. 2007. 53(6), 470-476.

  14. Lu Feng, Andrei V. Perepelov, Guang Zhao, Sergei D. Shevelev, Quan Wang, Sof’ya N. Senchenkova, Alexander S. Shashkov, Yunqi Geng, Peter R. Reeves, Yuriy A. Knirel, Lei Wang*. Structural and Genetic Evidence that the Escherichia coli O148 O Antigen is the Precursor of the Shigella dysenteriae type 1 O antigen and Identification of a Glucosyl Transferase Gene. Microbiology. 2007. 153(3-4), 139-47.

  15. Lothar Beutin, Quan Wang, Dieter Naumann, Weiqing Han, Gladys Krause, Luciana Leomil, Lei Wang, Lu Feng*. Relationship between O antigen subtypes, bacterial surface structures and O antigen gene clusters in Escherichia coli O123 strains carrying genes for Shiga-toxins and intimin. Journal of Medical Microbiology. 2007. 56(2), 177-184.

  16. Jiansong Cheng, Bin Liu, David A.Bastin, Weiqing Han, Lei Wang, Lu Feng*. Genetic characterization of the Escherichia coli O66 antigen and functional identification of its wzy gene. Journal of Microbiology. 2007.45(1), 69-74.

  17. Lu Feng, Wei Wang, Jiansong Cheng, Yi Ren, Guang Zhao, Chunxu Gao, Yun Tang, Xueqian Liu, Weiqing Han, Xia Peng, Rulin Liu, Lei Wang*. Genome and proteome of long-chain alkane degrading Geobacillus thermodenitrificans NG80-2 isolated from a deep-subsurface oil reservoir. Proceedings National Academy of Sciences of the United States of America. 2007.104(13): 5602-5607.

  18. Ying Wang, Yanli Xu, Andrei V. Perepelov, Yuanyuan Qi, Yuriy A. Knirel, Lei Wang, Lu Feng*. Biochemical Characterization of dTDP-D-Qui4N and dTDP-D-Qui4NAc Biosynthetic Pathways in Shigella dysenteriae type 7 and Escherichia coli O7. Journal of Bacteriology. 2007.189(23), 8626-35.

  19. Quan Wang, Min Wang, Fanrong Kong, Gwendolyn L. Gilbert, Boyang Cao, Lei Wang, Lu Feng*. Development of a DNA microarray to identify the Streptococcus pneumoniae serotypes contained in the 23-valent pneumococcal polysaccharide vaccine and closely related serotypes. Journal of Microbiological Methods. 2007.68(1), 128-136.

  20. Lu Feng*, Bin Liu, Yanqun Liu, Yuli A. Ratiner, Bo Hu, Dan Li, Xiaolin Zong, Wei Xiong, Lei Wang*. A Genomic Islet Mediates Flagellar Phase Variation in Escherichia coli Strains Carrying the Flagellin-Specifying Locus flk. Journal of Bacteriology. 2008. 190(13), 4470-7.

  21. Inka Brockhausen, Bo Hu, Bin Liu, Kenneth Lau, Walter A. Szarek, Lei Wang, Lu Feng*. Characterization of two 1,3-glucosyltransferases from Escherichia coli serotypes O56 and O152. Journal of Bacteriology. 2008. 190(14), 4922-4932.

  22. Quan Wang, Peng Ding, Andrei V. Perepelov, Yanli Xu, Ying Wang, Yuriy A. Knirel, Lei Wang, Lu Feng*. Characterization of dTDP-D-fucofuranose biosynthetic pathway in Escherichia coli O52. Molecular Microbiology. 2008. 70(6), 1358-1367.

  23. Lu Feng, Peter R. Reeves, Ruiting Lan, Yi Ren, Chunxu Gao, Zhemin Zhou, Yan Ren, Jiansong Cheng, Wei Wang, Jianmei Wang, Wubin Qian, Dan Li, Lei Wang*. A recalibrated molecular clock and independent origins for the cholera pandemic clones. PLoS ONE. 2008. 3(12), e4053.

  24. Xueqian Liu, Chunxu Gao, Aixiang Zhang, Peng Jin, Lei Wang, Lu Feng*. The nos gene cluster from gram-positive bacterium Geobacillus thermodenitrificans NG80-2 and functional characterization of the recombinant NosZ. FEMS Microbiology Letters. 2008. 289(1), 46-52.

  25. Min Wang, Boyang Cao, Qunfang Yu, Lei Liu, Qili Gao, Lei Wang, Lu Feng*. Analysis of the 16S–23S rRNA Gene Internal Transcribed Spacer Region in Klebsiella Species. Journal of Clinical Microbiology. 2008. 46(11), 3555-63.

  26. Xueqian Liu, Yanpeng Dong, Jing Zhang, Aixiang Zhang, Lei Wang, Lu Feng*. Two novel metal-independent long-chain alkyl alcohol dehydrogenases from Geobacillus thermodenitrificans NG80-2. Microbiology. 2009. 155(pt6), 2078-85.

  27. Xueqian Liu, Yangpeng Dong, Xiaomin Li, Yi Ren, Yanxia Li, Wei Wang, Lei Wang, Lu Feng*. Characterization of the anthranilate degradation pathway in Geobacillus thermodenitrificans NG80-2. Microbiology. 2010. 156, 589-595.

  28. Xiaomin Li, Yanxia Li, Dongmei Wei,Ping Li,Lei Wang,Lu Feng*. Characterization of a broad-range aldehyde dehydrogenase involved in alkane degradation in Geobacillus thermodenitrificans NG80-2. Microbiological Research. 2010 .165(8):706-12.

  29. Boyang Cao, Ting Ma, Yan Ren, Yi Ren, Guoqiang Li, Ping Li, Xi Guo, Peng Ding, and Lu Feng*.Complete genome sequence of Pusillimonas sp. T7-7, a cold-tolerant diesel oil-degrading bacterium isolated from the Bohai Sea in China. Journal of Bacteriology. 2011. 193(15):4021-2.

  30. Yanpeng Dong, Jiang Yan, Huiqian Du, Miao Chen, Ting Ma, Lu Feng*. Engineering of LadA for enhanced hexadecane oxidation using random- and site-directed mutagenesis . Applied Microbiology and Biotechnology. 2012,94(4): 1019-1029

  31. Quan Wang, Yanli Xu, Andrei V. Perepelov, Yuriy A. Knirel, Peter R. Reeves, Alexander S. Shashkov, Xi Guo, Peng Ding, Lu Feng*.Biochemical characterization of the CDP-D-arabinitol biosynthetic pathway in Streptococcus pneumoniae 17F. Journal of Bacteriology.2012, 194(8): 1868–1874.

  32. Yanxia Li, Junli Wu, Wei Wang, Peng Ding, Lu Feng*. Proteomics analysis of aromatic catabolic pathways in thermophilic Geobacillus thermodenitrificans NG80-2. Journal of Proteomics.2012, 75(4):1201-1210.

  33. Quan Wang , Yanli Xu , Andrei V Perepelov, Yuriy A Knirel, Peter R Reeves, Alexander S Shashkov, Peng Ding , Xi Guo and Lu Feng*. Characterization of the CDP-D-mannitol biosynthetic pathway in Streptococcus pneumoniae 35A. Glycobiology. 2012. 22(12):1760-7.

  34. Quan Wang , Andrei V Perepelov , Lothar Beutin, Sof'ya N Senchenkova, Yanli Xu, Alexander S Shashkov, Peng Ding, Yuriy A Knirel and Lu Feng*. Structural and genetic characterization of the Escherichia coli O180 O antigen and identification of a UDP-GlcNAc 6-dehydrogenase. Glycobiology. 2012, 22(10):1321-31.

  35. Yanpeng Dong, Huiqian Du, Chunxu Gao, Ting Ma, Lu Feng*. Characterization of two long-chain fatty acid CoA ligases in the Gram-positive bacterium Geobacillus thermodenitrificans NG80-2. Microbiological Research. 2012, 167: 602-607.